FASL anticorps

N° du produit ABIN120319

Cet anticorps Souris Monoclonal détecte spécifiquement FASL dans FACS, IP et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour FASL anticorps (ABIN120319)

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FASL est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: 14C2

Détail du produit anti-FASL anticorps

Specificité: This antibody recognises the CD178 cell surface antigen. Clone 14C2 is not reported to have a blocking function. We recommend the use of SM2268LE for functional studies.

Purification: Affinity Chromatography on Protein G

Immunogène: Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, Results maybe enhanced using membrane permeabilisation. ELISA. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FASL

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Autre désignation: CD178 / Fas Ligand

Sujet: CD178 is a 40 kDa glycoprotein also known as Fas ligand (CD95L). CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.Synonyms: APT1LG1, APTL, Apoptosis antigen ligand, CD95L protein, FASL, FASLG, Fas antigen ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6

ID gène: 356

NCBI Accession: NP_000630

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity